Hi Sumit,
In this case, I would suggest that you run the SAP OEE Netweaver Configuration CTC again, and then execute SAP OEE Integration Configuration again as well. That should resolve the issue.
Make sure that you execute these one after the other, as the situation that you mentioned can occur if the IP address of the system changes (can happen if it's not static IP).
Hope this helps.
Regards,
Sulaksh