Hi Praveen,
First, I would suggest that you identify what version, and SP, of MII and ECC. Also the NW version and SP if applicable.
Second, use this custom Google search and terms MII, IDoc Listener, and perhaps SM59. There are many discussions on IDoc Listeners going back a number of years. Many of the issues with IDoc Listeners have not changed in most of that time, so look at the older ones as well. I presume that you found and are using my How to Send an IDoc from SAP ECC to the SAP MII IDoc Listener (MII 12.1 to ECC 6.0) to set up your Listener? If not, you should review your configuration and setup procedure against it.
I have not looked at MII 14.0 or 15.0, but understand that the configuration of Listeners really has not changed since MII 12.1. So the document is still applicable.
Third, roughly 90% of the problems experienced with IDoc Listeners involve multiple uses of the self registering ProgID. Deleting it in one place, generally does not work. Use it in one place only. Create a new ProgID for each separate Listener (either type) on each separate MII instance for each ECC instance. Save yourself a lot of headaches. Never, ever reuse ProgIDs!!!
Fourth, most of the other issues involve a PI/XI system in the middle. Those are a bit more complicated since they rely on getting the connection configuration set up properly in PI. Since I am not that familiar with PI systems (most times it is not involved with the Listeners), I generally have to get other experts involved. Sometimes a CSS ticket is required.
Regards, Mike
SAP P&I Technology RIG